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Author
The author is a paranoid, deranged and cynical misanthrope who records snippets of her life so that she will remember them when she grows old and withered. The identities of any names or initials on this blog are based on the assumptions of the reader unless otherwise specified, and the author claims no responsibility for them.
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The author somehow got into medical school. Yes, you of the general public, shudder and fear the wrath of an inept doctor.
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Chat area
An hour later, (needless to say, of some procrastination), I return in glory and triumph!
I have memorised the payoff phase of glycolysis too! :D
Okok, here goes.
6: Glyceraldehye 3-phosphate dehydrogenase. Dehydrogenase is basically oxidation. In this step, an inorganic phosphate is added to each glyceraldehyde 3-phosphate (rmb, there were 2 from the last step when dihydroxyacetone phosphate was turned into glyceraldehyde 3-phosphate by the fairy godmother triose phosphate isomerase), and NAD+ (electron carrier) accepts 2 hydride ions (1 proton, 2 electrons each) to form NADH + H+.
So the end product of the reaction is 2 of 1,3-biphosphoglycerate.
7: Phosphoglycerate kinase: a phosphate grp is cleaved off from 1,3-biphosphoglycerate and added to ADP, making it ATP and thus happy again. And the same as above, this happens for each 1,3-biphosphoglycerate.
8: Phosphoglycerate mutase: 3-phosphoglycerate is mutated into 2-phosphoglycerate.
9: Enolase: I don't know why I remember this one. It removes a H2O molecule from each 2-phosphoglycerate, making the end product phosphoenolpyruvate. The finishing line is close in sight.
10: Pyruvate kinase. Woohoo! Pyruvate is created! Of course, by cleaving off the phosphate group to make ADP happy again. End of story.
So overall reaction from prep stage till now:
Glucose + 2ATP + 2NAD+ + 2Pi -> 2 glyceraldehyde 3-phosphate (end of prep) -> 2NADH + 2H+ + 4 ATP + 2 H2O + 2 pyruvate (good things come in 2s)
Aka net gain of 2ATP (ATP is basically energy required for reactions).
Wtfbbq, I don't see how I'll remember this 2 hours later.
12:25 PM